Non-TTR mutations reported to the FAPWTR

Fibrinogen a-chain amyloidosis
Mutation Organ Year of first tx Hospital Country
Glu526Val Liver + kidney 1996 King´s College Hospital, London UK
  Liver + kidney, Liver alone 1999 Mayo Clinic College of Medicine, Rochester USA
Liver + kidney 2005 Lahey Medical Center, Burlington USA
Liver + kidney 2007 Queen Elizabeth Hospital, Birmingham UK
Liver + kidney 2013 Hospital Saint-Luc, Montreal Canada
Liver + kidney 2016 Hospital Paul Brousse, Paris France

Renal amyloidosis
Mutation Organ Year of first tx Hospital Country
Apo A1 Gly26Arg Liver + kidney 1999 Lahey Medical Center, Burlington USA
Liver + kidney, Liver alone 2003 London Health Sciences Centre, Ontario Canada
Liver + kidney 2009 Queen Elizabeth Hospital, Birmingham UK
Liver + kidney 2015 Hospital Paul Brousse, Paris France
  Liver + kidney 2019 Mayo Clinic College of Medicine, Rochester USA

Lysozyme amyloidosis
Mutation Organ Year of first tx Hospital Country
Asp67His Liver 2004 Queen Elizabeth Hospital, Birmingham UK